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Research

Faculty research covers a wide range of interests including structural bioinformatics, systems biology, cancer informatics, chemical informatics, epigenomics, phenomics, text mining and understanding, electronic health records, evidence-based medicine, human-computer interactions in health care, consumer informatics, patient safety, information retrievals, data mining and knowledge, discovery, and machine learning.

Labs and Centers

Bioinformatics and Systems Biology Laboratory (BSBL)

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The research in my group focuses on developing and applying statistical machine learning techniques to address the problems in molecular biology. Currently we are developing bioinformatics algorithms and tools for proteomics, systems biology, and genomics. We have active projects in protein structure prediction, protein interaction and docking, protein function prediction, biological sequence alignments, inference and simulation of biological networks, and machine learning ranking.

Dermatology Department Lab

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The faculty and staff at the University of Missouri's Department of Dermatology are dedicated to providing high quality dermatological care for our patients, exceptional educational experiences for our residents and students, and the ongoing pursuit of new knowledge and scholarship. We provide dermatology care for patients at University of Missouri Health Care Hospital and Clinics, the Harry S. Truman Memorial Veterans' Hospital, and the Ellis Fischel Cancer Center. We also have been conducting teledermatology clinics in rural, underserved areas of Missouri for over 15 years.

Diagnostic Cardiology

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Digital Biology Laboratory

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The research focus of Digital Biology Laboratory (DBL) is Bioinformatics and Computational Biology. We are interested in various topics including protein structure prediction, high-throughput biological data analyses, computational proteomics, in silico studies of plant, microbes, neural systems, and many more.

HIMSS

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HIMSS is a global, cause-based, not-for-profit organization focused on better health through information technology (IT). HIMSS leads efforts to optimize health engagements and care outcomes using information technology.

ICU Communication Patterns

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To study and observe comunication patterns among clinical team.

Kazic Lab

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Korkin Lab

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This group is involved in an interdisciplinary research focusing on the areas of (i) machine learning and pattern recognition, and (ii) computational biology and structural bioinformatics.

Medical and Biological Digital Library Research Lab

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Medical Backing Project

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Banks have a central role to play in the evolution of electronic business transformation in healthcare, mostly because of their traditional role as processers of the $2.5 trillion that the US spends in healthcare annually. This role places them in a central position for moving the business of healthcare from paper to digital processes - an area of innovation known as "medical banking".

Schultz-Appel Chemical Ecology Laboratory

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The Schultz-Appel Chemical Ecology Lab at the University of Missouri is directed by Dr. Jack C. Schultz and Dr. Heidi Appel of the Plant Sciences Division, College of Agriculture, Food and Natural Resources. Our lab addresses broad ecological and evolutionary questions in insect and plant science by using chemical, biochemical, and molecular methods.

Zou Lab

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We are developing computational methods to calculate binding free energies for ligand-receptor complexes. The derived energy models are applied to protein-substrate interactions, protein-protein interactions, and structure-based drug design. We are also developing new docking algorithms to account for protein flexibility. Methods used in our laboratory include computer modeling, simulation and graphics display. Additional application includes modeling of structure-function relationship of membrane proteins.

Wet Labs

Animal Genomics

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Welcome to animalgenomics@Mizzou. We envision using this site to disseminate information about our research program, which primarily focuses on beef and dairy cattle gene mapping although we have interests in other species (see projects). We are still developing the structure and content of the site so additional material will be posted in the near future. If you would like to be notified when we make major updates to the site please sign up for our newsletter to the left. We hope you find this information useful and welcome suggestions as to how to make it better.

Chemical Ecology Lab

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The Schultz-Appel Chemical Ecology Lab at the University of Missouri is directed by Jack Schultz and Heidi Appel of the Plant Sciences Division, College of Agriculture, Food and Natural Resources. Our lab addresses broad ecological and evolutionary questions in insect and plant science by using chemical, biochemical, and molecular methods.

MU Soybean Genomics Laboratory

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The laboratory is directed by Dr. Henry T. Nguyen, Missouri Soybean Merchandising Council (MSMC) Endowed Professor of Genetics and Soybean Biotechnology. Research interests in the laboratory focus on the molecular genetics of plant stress tolerance and the application of genomics and genetic engineering technologies to soybean improvement.

National Center for Soybean Biotechnology

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By conducting and providing research in soybean genomics and biotechnology, we contribute to the genetic improvement of soybeans for food, human health, and industrial uses, while increasing the profitability of the U.S. soybean industry.

Pires Lab

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Research in our lab broadly encompasses plant evolutionary biology from phylogenetic studies in plant diversity to genome-wide analyses of gene expression. Current investigations are directed at molecular systematics and comparative genomics, with a particular focus on the evolution and ecology of polyploid plants. Polyploidy, the process of genome doubling that gives rise to organisms with multiple sets of chromosomes, is a major evolutionary force in both plants and animals.

Plant Root Genomics Consortium

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Plant roots play a vital role in water and mineral acquisition, and are essential for plant growth and development. Under conditions of drought, roots can adapt to continue growth while at the same time producing and sending early warning signals to shoots which inhibit plant growth above ground. The plant root system, often referred to as "the hidden half," has received much less attention compared to the shoot. We have formed a Plant Root Genomics Consortium dedicated to root genetics and physiology. The aim of this consortium is to develop an understanding of the molecular mechanisms used by plant roots to acquire water and minerals from the soil, to elucidate the role roots play in adaptation to drought conditions, and to transfer this knowledge to crop improvement through biotechnology.

Tang Lab

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Situated in the new Schweitzer Hall Addition, Department of Biochemistry at the University of Missouri - Columbia, the Tang laboratory utilizes state-of-the-art nuclear magnetic resonance or NMR and various biochemical/biophysical/computational techniques to characterize macromolecular structure and dynamics in solution.

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