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Chi-Ren Shyu, Ph.D.

Professor & Director

Office: 241 Naka Hall

Phone: 882-9007


Lab URL:

Home Department: Electrical Engineering and Computer Science

Concentration: Bioinformatics, Health Informatics

Education: PhD, Purdue University

Chi-Ren Shyu received his MSEE and Ph.D. degrees in Electrical and Computer Engineering from Purdue University in 1994 and 1999, respectively. Upon completing one year of post-doctoral training at Purdue, he joined the Electrical Engineering and Computer Science Department at the University of Missouri-Columbia in October 2000. In addition to holding the Shumaker Endowed Professorship for Informatics, he is currently the Director of the MU Informatics Institute, a Ph.D. program in bioinformatics and health informatics.
As the founding director of the Medical and Biological Digital Library Research Lab, Dr. Shyu oversees the work of a crew of students on a variety of research projects in such areas as biomedical informatics, geospatial informatics, data mining, and computer vision. Project sponsors for his research include the National Science Foundation, the National Geospatial-Intelligence Agency, the National institute of Health, U.S. Department of Education, University of Missouri Research Board, University of Missouri- Columbia Research Council, and other organizations, both for-profit and non-profit.

Selected Publications

34 entries « 1 of 4 »


Spencer, M; Takahashi, N; Chakraborty, S; Miles, J; Shyu, C R

Heritable genotype contrast mining reveals novel gene associations specific to autism subgroups (Journal Article)

J Biomed Inform, 77 , pp. 50-61, 2018, ISSN: 1532-0480 (Electronic) 1532-0464 (Linking).

(Links | BibTeX)


Ersoy, I; Kovalenko, M; Shyu, C R; Hammer, R

Eye Gaze Pattern Analysis of Whole Slide Image Viewing Behavior in PathEdEx Platform (Journal Article)

Cambridge University Press, 2017.

(Links | BibTeX)

Phinney, M A; Zhuang, Y; Lander, S; Sheets, L; Parker, J C; Shyu, C R

Contrast Mining for Pattern Discovery and Descriptive Analytics to Tailor Sub-Groups of Patients Using Big Data Solutions (Journal Article)

Stud Health Technol Inform, 245 , pp. 544-548, 2017, ISSN: 0926-9630 (Print) 0926-9630 (Linking).

(Links | BibTeX)

Raju, M; Chisholm, M; Mosa, A M; Shyu, C R

Investigating Risk Factors for Cataract Using the Cerner Health Facts Database (Journal Article)

Journal of Eye & Cataract Surgery, 2017.


Sheets, L; Petroski, G F; Zhuang, Y; Phinney, M A; Ge, B; Parker, J C; Shyu, C R

Combining Contrast Mining with Logistic Regression To Predict Healthcare Utilization in a Managed Care Population (Journal Article)

Appl Clin Inform, 8 (2), pp. 430-446, 2017, ISSN: 1869-0327 (Electronic).

(Links | BibTeX)

Shin, D; Kovalenko, M; Ersoy, I; Li, Y; Doll, D; Shyu, C R; Hammer, R

PathEdEx - Uncovering High-explanatory Visual Diagnostics Heuristics Using Digital Pathology and Multiscale Gaze Data (Journal Article)

J Pathol Inform, 8 , pp. 29, 2017, ISSN: 2229-5089 (Print).

(Links | BibTeX)


Cao, H F; Li, Y; Allen, C M; Phinney, M A; Shyu, C R

Visual Reasoning Indexing and Retrieval Using In-Memory Computing (Journal Article)

International Journal of Semantic Computing, 10 (3), pp. 299-322, 2016, ISSN: 1793-351x.

(Links | BibTeX)

Cao, H F; Phinney, M; Petersohn, D; Merideth, B; Shyu, C R

Mining large-scale repetitive sequences in a MapReduce setting (Journal Article)

International Journal of Data Mining and Bioinformatics, 14 (3), pp. 210-228, 2016, ISSN: 1748-5673.

(Links | BibTeX)

Kuang, X; Dhroso, A; Han, J G; Shyu, C R; Korkin, D

DOMMINO 2.0: integrating structurally resolved protein-, RNA-, and DNA-mediated macromolecular interactions (Journal Article)

Database (Oxford), 2016 , 2016, ISSN: 1758-0463 (Electronic) 1758-0463 (Linking).

(Links | BibTeX)

Phinney, M; Lander, S; Spencer, M; Shyu, C R

Cartesian Operations on Distributed Datasets Using Virtual Partitioning (Journal Article)

Proceedings 2016 Ieee Second International Conference on Big Data Computing Service and Applications (Bigdataservice 2016), pp. 1-9, 2016.

(Links | BibTeX)

34 entries « 1 of 4 »