Soybean Knowledge Base (SoyKB) project finds and shares comprehensive genetic and genomic soybean data through support of NSF-sponsored XSEDE high performance computing. SoyKB helps scientists improve soybean traits. XSEDE Stampede supercomputer 370,000 core hour allocation used in resequencing of over 1,000 soybean germplasm lines. XSEDE ECSS established Pegasus workflow that optimized SoyKB for supercomputers. SoyKB migrated workflow to XSEDE Wrangler data intensive supercomputer.